Fluconazole  - MIC-distributions of clinical strains and reference strains

   

Susceptible

Indeterminate Resistant  
 MIC (mg/L)   <.064 .125 .25 .5 1 2 4 8 16 32 >32
C.albicans*   - 4 100 66 28 11 2 3 - - 3
C.glabrata*   - - - - - 2 1 4 12 26 26
C.parapsilosis   - 1 1 11 13 1 1 - - - 5
C.tropicalis   - - 4 5 5 - - 1 - - -
C.lusitaniae   - 1 - 2 2 - - - - - -
C.krusei   - - - - - - - - - 6 6
                         
**C.parapsilosis_ATCC_22019

2 - 8

          14 37 11      
**C.krusei ATCC 6258

16-64

                1 38 2

*The typical C.albicans and C.glabrata wild type distributions are well illustrated in the study by Hoban et al, 1997.

Boxes with blue colour: results from several international studies. Numbers in boxes are test results on clinical strains in laboratories represented on the subcommittee for AFST. 

**Repeated internal QC with ATCC-strains with NCCLS recommended ranges (also marked in red colour) and the distribution of test results from several laboratories. 

 

NRMM, 2008-02-29